Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0005890
Disease: Body Height
Body Height 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0424678
Disease: Lean body mass
Lean body mass 		0.100 GeneticVariation GWASCAT Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. 30593698

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0427460
Disease: Red cell distribution width determination
Red cell distribution width determination 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1304746
Disease: RDW - Red blood cell distribution width result
RDW - Red blood cell distribution width result 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1314691
Disease: Age at menarche
Age at menarche 		0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0037116
Disease: Silicosis
Silicosis 		0.020 Biomarker BEFREE However, whether ZC3H4 is involved in EMT during silicosis remains unclear. 30826420

2019
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.100 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.100 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.100 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		0.100 GeneticVariation GWASCAT Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits. 30289880

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0037116
Disease: Silicosis
Silicosis 		0.020 Biomarker BEFREE Our study elucidates a link between SiO<sub>2</sub>-induced macrophage activation and the circZC3H4 RNA/ZC3H4 pathway, thereby providing novel insight into the potential use of ZC3H4 to develop novel therapeutic strategies for silicosis.-Yang, X., Wang, J., Zhou, Z., Jiang, R., Huang, J., Chen, L., Cao, Z., Chu, H., Han, B., Cheng, Y., Chao, J. Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation. 29401612

2018
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1535926
Disease: Neurodevelopmental Disorders
Neurodevelopmental Disorders 		0.300 Biomarker CTD_human Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases. 28191889

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0037369
Disease: Smoking
Smoking 		0.100 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.100 GeneticVariation GWASCAT Exome-wide association study of plasma lipids in >300,000 individuals. 29083408

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement 		0.100 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement 		0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0018935
Disease: Hematocrit procedure
Hematocrit procedure 		0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C0518015
Disease: Hemoglobin measurement
Hemoglobin measurement 		0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016
Entrez Id: 23211
Gene Symbol: ZC3H4
ZC3H4
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016